New Melle is a small country community in St. Charles County, Missouri, United States. It was founded by settlers from Melle, Germany.
It is located about 37 miles west of St. Louis. The population was 475 at the 2010 census.
New Melle is in the Francis Howell School District. Elementary school students attend Daniel Boone Elementary, middle school students attend Francis Howell Middle School, and high school students attend Francis Howell High School.
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